The Environmental Molecular Sciences Laboratory (EMSL), a DOE Office of Science user facility, has opened its annual call for large-scale research proposals. Researchers are encouraged to submit proposals for leading-edge research activities that aim to advance scientific understanding in EMSL’s Biological and Environmental Sciences areas that are of interest to, or aligned with, those of DOE’s Office of Biological and Environmental Research and EMSL. Details regarding this year’s focused topics, as well as contact information and links to the review criteria and proposal package guidance for this call, are available on EMSL’s website. The call is open until 11 p.m. PST March 4, 2019.